Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA7 | P43166 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417053 | 1.00 | TSHR (0.48) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL9039761 | 0.92 | TSHR (0.46) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL28408947 | 0.85 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10ESR1LMNA | |
| SCHEMBL14384187 | 0.84 | TSHR (0.38) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL5187673 | 0.83 | TSHR (0.40) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL28890928 | 0.82 | TSHR (0.54) | TSHRALDH1A1HSD17B10ESR1CYP1A2 | |
| SCHEMBL28891457 | 0.80 | TSHR (0.58) | TSHRALDH1A1HSD17B10ESR1MAPT | |
| SCHEMBL28412005 | 0.80 | TSHR (0.58) | TSHRALDH1A1HSD17B10ESR1MAPT | |
| SCHEMBL28417766 | 0.80 | TSHR (0.58) | TSHRALDH1A1HSD17B10ESR1MAPT | |
| SCHEMBL28412415 | 0.80 | TSHR (0.58) | TSHRALDH1A1HSD17B10ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779015-B2 | Pesticide compositions | FUNDACIÓ CENTRE DE REGULACIÓ GENÓMICA (ES) | 2023-10-10 | — | — | US | disclosed |
| CN-109970708-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2022-06-21 | — | — | CN | disclosed |
| US-20200359621-A1 | PESTICIDE COMPOSITIONS | FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA (ES) | 2020-11-19 | — | — | US | disclosed |
| CN-106632744-B | Propylene polymerization catalyst, preparation method and application | 北京化工大学 | 2020-05-15 | — | — | CN | disclosed |
| EP-3488695-A1 | PESTICIDE COMPOSITIONS | Fundació Centre de Regulació Genòmica (ES) | 2019-05-29 | — | — | EP | disclosed |
| US-20180072726-A9 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2018-03-15 | — | — | US | disclosed |
| US-9725452-B2 | Substituted indoles and pyrroles as RIP kinase inhibitors | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160068531-A1 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160024098-A1 | HYBRID NECROPTOSIS INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| US-9200008-B2 | Heterocyclic compound and p27Kip1 degradation inhibitor | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140323489-A1 | HYBRID NECROPTOSIS INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-30 | — | — | US | disclosed |
| US-20130079306-A1 | HETEROCYCLIC COMPOUND AND p27Kip1 DEGRADATION INHIBITOR | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-28 | — | — | US | disclosed |
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | disclosed |
| US-7399782-B2 | Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2008-07-15 | — | — | US | disclosed |
| US-5565500-A | CURED PRODUCT OBTAINED BY HEATING MIXTURE OF EPOXY RESIN, VINYL ETHER OR VINYL ESTER, IRON-CONTAINING METALLOCENE | CIBA-GEIGY CORPORATION (US) | 1996-10-15 | — | — | US | disclosed |
| US-5371259-A | Photoinitiators | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| US-5091439-A | Using arene iron complex as curing agent | CIBA-GEIGY CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-5073476-A | Containing iron aromatic complex and oxidizer | CIBA-GEIGY CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| US-4957946-A | FERROCENE TYPE COMPLEXES, EPOXY RESINS, VINYL ETHERS AND VINYL ESTERS | CIGA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| US-4861806-A | PHOTOPOLYMERIZATION, LATENCY | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200359621-A1 | PESTICIDE COMPOSITIONS | ADH1C, DDT, AKR1C3 | TSHR 3247/4885ALDH1A1 35/4885HSD17B10 22/4885 |
| US-20160068531-A1 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | ZC3HAV1, IDO1, AZI2 | TSHR 1187/4885ALDH1A1 1795/4885HSD17B10 3620/4885 |
| US-20140323489-A1 | HYBRID NECROPTOSIS INHIBITORS | RIPK3, RIPK1, RIPK4 | TSHR 4186/4885ALDH1A1 4684/4885HSD17B10 3567/4885 |
| US-20130079306-A1 | HETEROCYCLIC COMPOUND AND p27Kip1 DEGRADATION INHIBITOR | CDKN1A, SKP2, CCNI | TSHR 4485/4885ALDH1A1 1594/4885HSD17B10 2262/4885 |
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | NEDD8, NAE1, UBA3 | TSHR 4279/4885ALDH1A1 398/4885HSD17B10 1884/4885 |
| US-20160024098-A1 | HYBRID NECROPTOSIS INHIBITORS | RIPK3, RIPK1, RIPK4 | TSHR 4186/4885ALDH1A1 4684/4885HSD17B10 3567/4885 |
| US-20180072726-A9 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | ZC3HAV1, IDO1, AZI2 | TSHR 1187/4885ALDH1A1 1795/4885HSD17B10 3620/4885 |
| US-11779015-B2 | Pesticide compositions | ADH1C, DDT, AKR1C3 | TSHR 3247/4885ALDH1A1 35/4885HSD17B10 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.