Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390175 | 1.00 | MAPT (0.59) | MAPTLMNATP53ABCG2POLB | |
| SCHEMBL29007280 | 0.89 | ADORA3 (0.57) | MAPTLMNATP53ABCG2POLB | |
| SCHEMBL30390170 | 0.87 | ABCG2 (0.60) | MAPTLMNATP53ABCG2KDM4E | |
| SCHEMBL29007307 | 0.87 | ABCG2 (0.60) | MAPTLMNATP53ABCG2KDM4E | |
| SCHEMBL30542071 | 0.85 | ABCG2 (0.59) | MAPTTP53ABCG2POLBNPY5R | |
| SCHEMBL29007295 | 0.78 | ADORA3 (0.59) | LMNAKDM4EALDH1A1ADORA3MAPK1 | |
| SCHEMBL4001283 | 0.78 | MAPT (0.67) | MAPTLMNATP53ABCG2POLB | |
| SCHEMBL6001949 | 0.77 | TUBB4A (0.54) | MAPTTP53ABCG2POLBADORA3 | |
| SCHEMBL29256144 | 0.75 | KDM4E (0.56) | MAPTLMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL8619064 | 0.75 | MEN1 (0.64) | MAPTLMNATP53ABCG2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960046-A | Preparation method of 1-amino substituted isoquinoline substances | 温州大学 | 2023-04-14 | — | — | CN | disclosed |