Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926769 | 0.80 | CREBBP (0.34) | KDM4EMEN1KMT2ANPC1MAPT | |
| SCHEMBL27740237 | 0.76 | CMA1 (0.34) | MEN1KMT2ACYP1A2 | |
| SCHEMBL27437424 | 0.76 | TDP1 (0.35) | KDM4EMEN1KMT2AMAPTGAA | |
| Methylamine SCHEMBL27568812 | 0.76 | BRD4 (0.35) | MEN1KMT2ANPC1MAPTGAA | |
| SCHEMBL29036195 | 0.74 | PDE3B (0.41) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| Methylamine SCHEMBL27587572 | 0.74 | KDM4E (0.33) | KDM4EMEN1KMT2AMAPTGAA | |
| SCHEMBL29007525 | 0.71 | CYP11B1 (0.38) | KDM4EMEN1KMT2ANPC1MAPT | |
| SCHEMBL27995173 | 0.71 | KDM4E (0.37) | KDM4EMEN1KMT2ANPC1MAPT | |
| SCHEMBL28461171 | 0.66 | KDM4E (0.50) | KDM4EMEN1KMT2ANPC1MAPT | |
| SCHEMBL29007518 | 0.65 | CYP11B1 (0.70) | KDM4EMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199674-A | Rhodamine fluorescence quenching agent based on torsion intramolecular charge transfer, synthesis and application | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-116199674-A | Rhodamine fluorescence quenching agent based on torsion intramolecular charge transfer, synthesis and application | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | disclosed |