Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL27568812 | 0.94 | BRD4 (0.35) | CREBBPBRD4EP300BRPF1MEN1 | |
| SCHEMBL29007498 | 0.80 | KDM4E (0.51) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL27322746 | 0.80 | MEN1 (0.33) | CREBBPBRD4EP300MEN1KMT2A | |
| SCHEMBL29036205 | 0.77 | CHRNB2 (0.31) | KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL27740237 | 0.77 | CMA1 (0.34) | BRD4MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL27437424 | 0.77 | TDP1 (0.35) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL27687954 | 0.75 | SMARCA2 (0.31) | — | |
| SCHEMBL29036195 | 0.74 | PDE3B (0.41) | MAPTKDM4ECYP1A2CYP2C19SMN1; SMN2 | |
| Methylamine SCHEMBL27587572 | 0.74 | KDM4E (0.33) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL29576846 | 0.73 | CREBBP (0.47) | CREBBPBRD4EP300BRPF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878026-A | Pharmacological adjunctive therapy associated with glaucoma filtration surgery | BAUSCH & LOMB | 2010-11-03 | — | — | CN | claimed |
| CN-101578281-A | Synthesis of selected stereoisomers of certain substituted alcohols | BAUSCH & LOMB (US) | 2009-11-11 | — | — | CN | claimed |
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | claimed |
| CN-101535239-A | Synthesis of selected stereoisomers of certain substituted alcohols | BAUSCH & LOMB (US) | 2009-09-16 | — | — | CN | claimed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | claimed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | claimed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | claimed |
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | claimed |
| CN-1735599-A | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands | BOEHRINGER INGELHEIM PHARMA (US) | 2006-02-15 | — | — | CN | claimed |
| CN-1402720-A | 2,4-diaminopyrimidine compounds useful as immunosuppressants | PFIZER PROD INC (US) | 2003-03-12 | — | — | CN | claimed |
| CN-113024554-B | Preparation method of rumepilone intermediate | 上海法默生物科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-114853684-A | Purification method of Lomepilon intermediate | 北京万全德众医药生物技术有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-113024554-A | Preparation method of rumepilone intermediate | 上海法默生物科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-106659717-B | Tricyclic nitrogen-containing compounds for the treatment of neisseria gonorrhoeae infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-108602835-A | Pde1 inhibitor | 伊莱利利公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-1402720-A | 2,4-diaminopyrimidine compounds useful as immunosuppressants | PFIZER PROD INC (US) | 2003-03-12 | — | — | CN | disclosed |
| CN-1351498-A | Pyrrolotriazines inhibitors of kinases | BRISTOL MYERS SQUIBB CO (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1058710-C | New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1108935-A | Composition preparation containing quinoxaline and nucleoside | HOECHST AG (DE) | 1995-09-27 | — | — | CN | disclosed |
| CN-1098406-A | New benzamide derivatives and method for making thereof and the pharmaceutical composition that contains them | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-02-08 | — | — | CN | disclosed |