Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765728 | 0.83 | PDE2A (0.52) | PDE2A | |
| SCHEMBL1970199 | 0.83 | PDE2A (0.52) | PDE2AKDM1AHAO1PTGS1AKR1C3 | |
| SCHEMBL21875040 | 0.77 | IDO1 (0.41) | PDE2AIDO1 | |
| SCHEMBL17431626 | 0.73 | PDE2A (0.46) | PDE2AKDM1AHAO1PTGS1AKR1C3 | |
| SCHEMBL944794 | 0.71 | PDE2A (0.44) | PDE2AIDO1KDM1AHAO1PTGS1 | |
| SCHEMBL64710 | 0.71 | — | — | |
| SCHEMBL18656576 | 0.69 | PDE2A (0.42) | PDE2AKDM1AHAO1PTGS1AKR1C3 | |
| SCHEMBL21875032 | 0.69 | PDE2A (0.32) | PDE2A | |
| SCHEMBL21585264 | 0.69 | PDE2A (0.48) | PDE2AKDM1AHAO1PTGS1AKR1C3 | |
| SCHEMBL517877 | 0.69 | PDE2A (0.42) | PDE2AKDM1AHAO1PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185742-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2021-11-30 | — | — | US | claimed |
| EP-3677318-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2021-05-05 | — | — | EP | claimed |
| EP-3677318-A1 | GOLF BALL | Sumitomo Rubber Industries, Ltd. (JP) | 2020-07-08 | — | — | EP | claimed |
| US-20200129813-A1 | GOLF BALL | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2020-04-30 | — | — | US | claimed |
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-11185742-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2021-11-30 | — | — | US | disclosed |
| EP-3677318-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2021-05-05 | — | — | EP | disclosed |
| EP-3677318-A1 | GOLF BALL | Sumitomo Rubber Industries, Ltd. (JP) | 2020-07-08 | — | — | EP | disclosed |
| EP-1658266-B1 | PENTAFLUOROSULFANYL PHENYL-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING SAID COMPOUNDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| US-7381841-B2 | Cardiovascular disorders; antiischemic agenst | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| US-7381841-B2 | Cardiovascular disorders; antiischemic agenst | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| US-7381841-B2 | Cardiovascular disorders; antiischemic agenst | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| EP-1658266-A1 | PENTAFLUOROSULFANYL PHENYL-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING SAID COMPOUNDS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005021492-A1 | PENTAFLUOROSULFANYL PHENYL-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING SAID COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-03-10 | — | — | WO | disclosed |
| WO-2005021492-A1 | PENTAFLUOROSULFANYL PHENYL-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING SAID COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-03-10 | — | — | WO | disclosed |
| US-20050043401-A1 | Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043401-A1 | Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them | TNNI3, TNNT2, RYR2 | PDE2A 1587/4885IDO1 3578/4885KDM1A 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.