SCHEMBL1970199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17431626	0.89	PDE2A (0.46)	PDE2AKDM1AHAO1AKR1C3AKR1C2
	SCHEMBL944794	0.86	PDE2A (0.44)	PDE2AKDM1AHAO1AKR1C3AKR1C2
	SCHEMBL944658	0.83	LMNA (0.50)	PDE2AKDM1AHAO1
	SCHEMBL50457	0.83	ALOX15 (0.50)	PDE2AKDM1A
	SCHEMBL817545	0.83	ACHE (0.50)	PDE2AKDM1A
	SCHEMBL2900759	0.83	PDE2A (0.42)	PDE2AKDM1AHAO1AKR1C3AKR1C2
	SCHEMBL472361	0.83	PDE2A (0.42)	PDE2AKDM1AHAO1AKR1C3AKR1C2
	SCHEMBL240645	0.83	MEN1 (0.50)	PDE2AKDM1A
	SCHEMBL21585264	0.83	PDE2A (0.48)	PDE2AKDM1AHAO1AKR1C3AKR1C2
	SCHEMBL2109	0.83	CYP2A6 (0.50)	PDE2AKDM1AHAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.