Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5659578 | 0.78 | CA2 (0.50) | CTBP2 | |
| Trifluoroacetic Acid SCHEMBL29484054 | 0.78 | TAAR1 (0.64) | SMN1; SMN2FFAR1MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29484053 | 0.78 | TAAR1 (0.64) | SMN1; SMN2FFAR1MEN1KMT2AALDH1A1 | |
| Parachlorophenol SCHEMBL27659204 | 0.75 | MAPK1 (0.56) | MIFSMN1; SMN2PPARAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4544157 | 0.75 | SLC6A4 (0.58) | PPARGPPARAGRB2 | |
| Chlorobenzene SCHEMBL11116080 | 0.74 | TSHR (0.55) | PPARGPPARAMEN1KMT2AALDH1A1 | |
| SCHEMBL28675261 | 0.74 | IDO1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28675263 | 0.74 | IDO1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL25267515 | 0.74 | PPARG (0.45) | MIFSMN1; SMN2PPARGPPARAMEN1 | |
| SCHEMBL25224016 | 0.74 | PPARG (0.45) | MIFSMN1; SMN2PPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114988981-A | Preparation method of alpha-trifluoromethyl arylpropyne compound | 盐城工学院 | 2022-09-02 | — | — | CN | disclosed |