Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416796 | 1.00 | STAT3 (0.40) | STAT3EGLN1NPC1RETKDM4E | |
| SCHEMBL30180890 | 1.00 | STAT3 (0.40) | STAT3EGLN1NPC1RETKDM4E | |
| SCHEMBL30181102 | 0.89 | NPC1 (0.45) | NPC1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL29007911 | 0.89 | NPC1 (0.45) | NPC1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL29007976 | 0.84 | NPC1 (0.41) | NPC1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30181266 | 0.84 | NPC1 (0.41) | NPC1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30417628 | 0.82 | MAPK8 (0.39) | NPC1KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL29007745 | 0.80 | LMNA (0.48) | KDM4EHPGDALDH1A1HSD17B10KMT2A | |
| SCHEMBL30417566 | 0.78 | ELANE (0.46) | KMT2AHTTMEN1 | |
| SCHEMBL29007784 | 0.77 | LMNA (0.43) | KDM4EHPGDALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |