Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL5829465 | 0.90 | TDP1 (0.77) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL8081763 | 0.90 | TDP1 (0.77) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL20478 | 0.90 | — | — | |
| Propylene Glycol SCHEMBL4185035 | 0.90 | — | — | |
| Propylene Glycol SCHEMBL8072957 | 0.90 | TDP1 (0.77) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL28302926 | 0.90 | TDP1 (0.77) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL19462749 | 0.87 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL19462566 | 0.87 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL27529046 | 0.87 | — | — | |
| Propylene Glycol SCHEMBL560576 | 0.84 | TDP1 (0.67) | TDP1TSHRALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023863-B | Quick-curing and easy-to-detach thread locking anaerobic adhesive and preparation method thereof | 武汉中科先进材料科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-116023863-A | Quick-curing and easy-to-detach thread locking anaerobic adhesive and preparation method thereof | 武汉中科先进材料科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023863-B | Quick-curing and easy-to-detach thread locking anaerobic adhesive and preparation method thereof | 武汉中科先进材料科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-116023863-A | Quick-curing and easy-to-detach thread locking anaerobic adhesive and preparation method thereof | 武汉中科先进材料科技有限公司 | 2023-04-28 | — | — | CN | disclosed |