SCHEMBL29009407

SCHEMBL29009407

CCCCc1c(C(N)=O)ccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.54
CNR1 P21554 8/20 0.43
CNR2 P34972 7/20 0.43
SLC6A3 Q01959 2/20 0.42
MEN1 O00255 1/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CYP2C9 P11712 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9794886 0.95 NCEH1 (0.50) NCEH1CNR1CNR2SLC6A3MEN1
SCHEMBL4948479 0.94 NCEH1 (0.49) NCEH1CNR1CNR2SLC6A3MEN1
SCHEMBL17592082 0.91 NCEH1 (0.52) NCEH1CNR1CNR2MEN1MAPT
SCHEMBL14150812 0.86 NCEH1 (0.56) NCEH1CNR1CNR2CYP2C9KDM4E
SCHEMBL21569594 0.86 NCEH1 (0.56) NCEH1CNR1CNR2MAPTCYP2C9
SCHEMBL11594011 0.84 NCEH1 (0.50) NCEH1MEN1MAPTKMT2ACYP2C9
SCHEMBL11776927 0.84 CNR2 (0.44) NCEH1CNR1CNR2MEN1MAPT
SCHEMBL11115871 0.82 WDR5 (0.51) NCEH1CNR1CNR2CYP2C9KDM4E
SCHEMBL9781027 0.82 MEN1 (0.45) CNR1CNR2SLC6A3MEN1NR1I2
SCHEMBL3157876 0.81 WDR5 (0.50) NCEH1CNR1CNR2CYP2C9WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974711-A Preparation method of aryl amide compound by using aromatic ester catalytically activated by boron salt 湖南农业大学 2023-04-18 CN disclosed