Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534893 | 0.92 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL27265024 | 0.92 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL29074022 | 0.92 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL8780461 | 0.92 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL1049187 | 0.92 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL28409459 | 0.89 | KMT2A (0.42) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL28927012 | 0.89 | GABRP (0.41) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL2972655 | 0.88 | LMNA (0.50) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL2488526 | 0.88 | MEN1 (0.41) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL28273750 | 0.87 | ALDH1A1 (0.41) | MEN1KMT2AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |