Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837258 | 0.81 | LMNA (0.39) | LMNATRPM8KDM4EKMT2AFFAR1 | |
| SCHEMBL29837167 | 0.80 | METAP1 (0.35) | LMNATRPM8KMT2ANR3C1 | |
| SCHEMBL1896858 | 0.80 | LMNA (0.53) | LMNATRPM8NPC1RAB9AAURKA | |
| SCHEMBL16180417 | 0.79 | LMNA (0.43) | LMNATRPM8NPC1RAB9AAURKA | |
| SCHEMBL29009669 | 0.74 | HTT (0.44) | LMNATRPM8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29009670 | 0.74 | DAO (0.35) | LMNANPC1RAB9ATP53KMT2A | |
| SCHEMBL2092783 | 0.72 | NPSR1 (0.50) | TRPM8NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2772989 | 0.71 | LMNA (0.51) | LMNATRPM8NPC1RAB9AAURKA | |
| SCHEMBL2772986 | 0.71 | LMNA (0.51) | LMNATRPM8NPC1RAB9AAURKA | |
| SCHEMBL1325354 | 0.71 | LMNA (0.51) | LMNATRPM8NPC1RAB9AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |