Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935444 | 0.82 | HTT (0.54) | HTTNPSR1TSHRPOLBTP53 | |
| SCHEMBL29837150 | 0.79 | POLB (0.39) | HTTNPSR1TSHRPOLBTP53 | |
| SCHEMBL10855054 | 0.78 | NPSR1 (0.50) | HTTNPSR1TSHRPOLBTP53 | |
| SCHEMBL2092783 | 0.75 | NPSR1 (0.50) | HTTNPSR1TSHRPOLBALDH1A1 | |
| SCHEMBL29009656 | 0.74 | LMNA (0.43) | TP53KMT2AKDM4ETRPM8SMN1; SMN2 | |
| SCHEMBL28842772 | 0.73 | ALDH1A1 (0.37) | TSHRPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15348824 | 0.72 | TSHR (0.50) | HTTNPSR1TSHRPOLBALDH1A1 | |
| SCHEMBL7904906 | 0.71 | KMT2A (0.54) | HTTNPSR1TSHRPOLBALDH1A1 | |
| SCHEMBL2954353 | 0.70 | TSHR (0.51) | HTTNPSR1TSHRPOLBALDH1A1 | |
| SCHEMBL6272956 | 0.70 | HTT (0.53) | HTTNPSR1TSHRPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |