Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009675 | 0.89 | TP53 (0.41) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL5518969 | 0.81 | ALDH1A1 (0.49) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL29837177 | 0.80 | TP53 (0.43) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL30957339 | 0.80 | NPC1 (0.51) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL5514063 | 0.80 | NPC1 (0.51) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL30957315 | 0.79 | NPC1 (0.50) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL30957337 | 0.79 | NPC1 (0.50) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL11851073 | 0.79 | ALDH1A1 (0.46) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL894066 | 0.78 | NPC1 (0.69) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL11516433 | 0.78 | ALDH1A1 (0.49) | TP53ALDH1A1NPC1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |