SCHEMBL29009803

SCHEMBL29009803

Cc1ccc(C(F)F)c(C)c1CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 5/20 0.36
MAPT P10636 5/20 0.36
GAA P10253 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
SLC22A12 Q96S37 2/20 0.36
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 2/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
FFAR1 O14842 1/20 0.35
SLC26A3 P40879 2/20 0.34
POLB P06746 1/20 0.33
AGBL2 Q5U5Z8 1/20 0.33
GLA P06280 1/20 0.32
STING1 Q86WV6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426974 1.00 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL1258872 0.79 CYP1A2 (0.50) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL29009829 0.75 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL1004496 0.73 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL12952514 0.73 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL1003898 0.73 AKR1B1 (0.52) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL17536174 0.72 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL29010104 0.71 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL861566 0.69 PTGS1 (0.51) CYP1A2CYP3A4CYP2C19KDM4EMAPT
SCHEMBL1004061 0.69 MAPT (0.47) CYP1A2CYP3A4CYP2C19MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed