Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004061 | 0.85 | MAPT (0.47) | PTGS1PTGDR2SMN1; SMN2POLBCA12 | |
| SCHEMBL12479163 | 0.85 | CA12 (0.47) | PTGS1PTGDR2CA12CA9KDM4E | |
| SCHEMBL10978468 | 0.84 | KDM4E (0.43) | PTGS1SMN1; SMN2PDCD1CD274GAA | |
| SCHEMBL27839247 | 0.83 | PTGS1 (0.49) | PTGS1PTGDR2TP53SMN1; SMN2POLB | |
| SCHEMBL6027622 | 0.82 | PDCD1 (0.53) | PTGS1SMN1; SMN2POLBPDCD1CD274 | |
| SCHEMBL10755148 | 0.80 | PDCD1 (0.43) | PTGS1POLBPDCD1CD274KDM4E | |
| SCHEMBL1258872 | 0.79 | CYP1A2 (0.50) | PTGS1SMN1; SMN2POLBGAAKDM4E | |
| SCHEMBL31514218 | 0.78 | MEN1 (0.39) | PTGS1SMN1; SMN2PDCD1CD274GAA | |
| SCHEMBL845280 | 0.78 | PDCD1 (0.44) | PTGS1TP53POLBPDCD1CD274 | |
| SCHEMBL10978479 | 0.78 | ALDH1A1 (0.49) | PTGS1SMN1; SMN2PDCD1CD274KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |
| WO-2017184589-A1 | A VERSATILE LIGAND FOR PALLADIUM-CATALYZED META-C-H FUNCTIONALIZATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-26 | — | — | WO | disclosed |
| CN-103980109-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | 拜尔农作物科学股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-103980109-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | 拜尔农作物科学股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-103980109-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-08-13 | — | — | CN | disclosed |
| CN-103980109-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-08-13 | — | — | CN | disclosed |
| CN-103980109-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-08-13 | — | — | CN | disclosed |
| CN-102471215-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| CN-102471215-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| CN-102471215-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| US-8664428-B2 | Method for producing (2,4-dimethylbiphenyl-3-yl)acetic acids, the esters thereof and intermediate compounds | BAYER CROPSCIENCE AG (DE) | 2014-03-04 | — | — | US | disclosed |
| CN-102471215-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2012-05-23 | — | — | CN | disclosed |
| CN-102471215-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2012-05-23 | — | — | CN | disclosed |
| EP-2451767-A2 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20120116118-A1 | Method for Producing (2,4-Dimethylbiphenyl-3-yl)Acetic Acids, the Esters Thereof and Intermediate Compounds | BAYER CROPSCIENCE AG (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120116118-A1 | Method for Producing (2,4-Dimethylbiphenyl-3-yl)Acetic Acids, the Esters Thereof and Intermediate Compounds | BAYER CROPSCIENCE AG (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120116118-A1 | Method for Producing (2,4-Dimethylbiphenyl-3-yl)Acetic Acids, the Esters Thereof and Intermediate Compounds | BAYER CROPSCIENCE AG (DE) | 2012-05-10 | — | — | US | disclosed |
| WO-2011003530-A8 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011003530-A3 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011003530-A2 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116118-A1 | Method for Producing (2,4-Dimethylbiphenyl-3-yl)Acetic Acids, the Esters Thereof and Intermediate Compounds | DDC, DDT, PAH | PTGS1 3663/4885PTGDR2 1104/4885TP53 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.