Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535414 | 0.82 | MAPK1 (0.42) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL5729208 | 0.78 | NFKB1 (0.37) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL27670508 | 0.77 | MAPK1 (0.37) | MAPK1NFKB1NFKB2RELACHRM3 | |
| SCHEMBL27995523 | 0.77 | NFKB1 (0.35) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL31605677 | 0.75 | MAPK1 (0.35) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL8880070 | 0.74 | — | — | |
| SCHEMBL18108616 | 0.74 | MAPK1 (0.34) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL5837950 | 0.72 | HRH3 (0.45) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL18024844 | 0.72 | EPHX1 (0.37) | MAPK1NFKB1NFKB2RELAHRH3 | |
| SCHEMBL16086104 | 0.72 | EPHX1 (0.37) | MAPK1NFKB1NFKB2RELAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382514-B | Prodrugs of HCV NS5B polymerase inhibitors and methods of making and using the same | 亚历山大·瓦西里耶维奇·伊瓦切恩科 | 2023-06-02 | — | — | CN | disclosed |