Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010498 | 0.77 | MAPK1 (0.43) | MAPK1NFKB1NFKB2RELAMAPT | |
| SCHEMBL27363208 | 0.74 | — | — | |
| SCHEMBL2535414 | 0.73 | MAPK1 (0.42) | MAPK1NFKB1NFKB2RELACHRM3 | |
| SCHEMBL20766890 | 0.71 | MAPK1 (0.36) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL23166480 | 0.71 | — | — | |
| SCHEMBL1034237 | 0.71 | HRH3 (0.41) | MAPK1MAPTCHRM3 | |
| SCHEMBL951872 | 0.71 | HRH3 (0.41) | MAPK1MAPTCHRM3 | |
| SCHEMBL1415306 | 0.71 | HRH3 (0.41) | MAPK1MAPTCHRM3 | |
| SCHEMBL292850 | 0.70 | HSD17B10 (0.37) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL2536402 | 0.69 | CHRNB2 (0.40) | CHRM3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1894206-A | N-substituted N-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2007-01-10 | — | — | CN | disclosed |