Diphenylsulfane

Diphenylsulfane

SCHEMBL2901074

CCCCCCCCCCCCc1ccccc1S(=O)(=O)Oc1ccc(Sc2ccccc2)cc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
CYSLTR2 Q9NS75 6/20 0.38
CYSLTR1 Q9Y271 6/20 0.38
LIPG Q9Y5X9 1/20 0.38
STS P08842 1/20 0.37
PPARA Q07869 2/20 0.36
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL2896008 0.93 BID (0.38) CYSLTR2CYSLTR1LIPGPPARABID
Diphenylsulfane SCHEMBL4425601 0.92 STS (0.44) NR1H2NR1H3CYSLTR2CYSLTR1LIPG
Diphenylsulfane SCHEMBL2895610 0.92 NR1H2 (0.34) NR1H2NR1H3CYSLTR2CYSLTR1LIPG
SCHEMBL4599603 0.88 LIPG (0.44) NR1H2NR1H3CYSLTR2CYSLTR1LIPG
SCHEMBL28991878 0.88 LIPG (0.44) NR1H2NR1H3CYSLTR2CYSLTR1LIPG
Iodobenzene SCHEMBL2898486 0.83 PPARA (0.40) LIPGPPARABIDMCL1BCL2L1
Hydrogen Sulfide SCHEMBL16581546 0.81 STS (0.49) NR1H2NR1H3LIPGSTSPPARA
Iodide SCHEMBL15055563 0.81 STS (0.49) NR1H2NR1H3LIPGSTSPPARA
Iodobenzene SCHEMBL2895972 0.79 HTT (0.44)
SCHEMBL11588820 0.77 LIPG (0.49) NR1H2NR1H3CYSLTR2CYSLTR1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253470-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-06-16 EP disclosed
EP-1270553-B1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORP (JP) 2009-11-18 EP disclosed
US-6846607-B2 Carbazole derivative and chemically amplified radiation-sensitive resin composition JSR CORPORATION (JP) 2005-01-25 US disclosed
US-6770780-B1 QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS JSR CORPORATION (JP) 2004-08-03 US disclosed
EP-1343048-A2 Anthracene derivative and radiation-sensitive resin composition JSR Corporation (JP) 2003-09-10 EP disclosed
EP-1270553-A2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR Corporation (JP) 2003-01-02 EP disclosed
EP-1253470-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-10-30 EP disclosed
EP-1231205-A1 VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2002-08-14 EP disclosed