Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.81 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010889 | 0.90 | TNKS2 (1.00) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010888 | 0.89 | TNKS2 (0.83) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010899 | 0.88 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010900 | 0.88 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010780 | 0.85 | TNKS2 (0.76) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010777 | 0.81 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL28992919 | 0.79 | ALDH1A1 (0.69) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL30230292 | 0.79 | ALDH1A1 (0.69) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010896 | 0.78 | TNKS2 (0.83) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL13604402 | 0.74 | TNKS2 (0.64) | TNKS2ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | claimed |
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |