Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 13/20 | 0.76 |
| ▸ | TNKS | O95271 | 1/20 | 0.58 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010900 | 0.87 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010899 | 0.87 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010889 | 0.87 | TNKS2 (1.00) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010888 | 0.86 | TNKS2 (0.83) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010776 | 0.85 | TNKS2 (0.81) | TNKS2EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL29010782 | 0.82 | EGFR (0.77) | TNKS2TNKSPARP3EGFRALDH1A1 | |
| SCHEMBL29010909 | 0.79 | TNKS2 (0.78) | TNKS2TNKSPARP3EGFRALDH1A1 | |
| SCHEMBL15033492 | 0.76 | TNKS2 (0.60) | TNKS2TNKSPARP3ALDH1A1KDM4E | |
| SCHEMBL7670240 | 0.75 | TNKS2 (0.65) | TNKS2TNKSPARP3ALDH1A1KDM4E | |
| SCHEMBL3770937 | 0.73 | RXRA (0.54) | KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |