Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18938465 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL413228 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18934846 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18935496 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL13060381 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL24618011 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1678569 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6917808 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21212072 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1679607 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |