Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901239 | 0.82 | L3MBTL1 (0.51) | L3MBTL1ADORA2AADORA1CREBBPKCNH2 | |
| SCHEMBL2900642 | 0.78 | CREBBP (0.52) | L3MBTL1ADORA2AADORA1CREBBPMAPK1 | |
| SCHEMBL2900601 | 0.75 | NPC1 (0.38) | L3MBTL1CNR2ALDH1A1 | |
| SCHEMBL3289673 | 0.74 | L3MBTL1 (0.56) | L3MBTL1ADORA2AADORA1CREBBPCNR2 | |
| SCHEMBL10094636 | 0.73 | L3MBTL1 (0.59) | L3MBTL1ADORA2AADORA1CREBBPKDM5B | |
| SCHEMBL30980826 | 0.72 | PIM1 (0.43) | L3MBTL1KCNH2CNR2KDM5B | |
| SCHEMBL31276671 | 0.71 | CNR2 (0.48) | CNR2 | |
| SCHEMBL10094468 | 0.70 | L3MBTL1 (0.55) | L3MBTL1ADORA2AADORA1CREBBPKDM5B | |
| SCHEMBL4784136 | 0.69 | L3MBTL1 (0.60) | L3MBTL1ADORA2AADORA1CREBBPCYP2C9 | |
| SCHEMBL22349811 | 0.68 | CNR2 (0.42) | CNR2KDM5BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | L3MBTL1 1263/4885ADORA2A 536/4885ADORA1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.