Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 3/20 | 0.59 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CBS | P35520 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455030 | 0.82 | KMT2A (0.59) | SLC5A1SLC5A2GAAMAPTTDP1 | |
| SCHEMBL457058 | 0.81 | SLC5A1 (0.52) | SLC5A1SLC5A2GAAMAPTTDP1 | |
| SCHEMBL13978646 | 0.78 | KMT2A (0.66) | MAPTTDP1APPKMT2AKEAP1 | |
| SCHEMBL17203216 | 0.77 | TDP1 (0.41) | SLC5A1SLC5A2GAAMAPTTDP1 | |
| SCHEMBL22499185 | 0.77 | TDP1 (0.58) | MAPTTDP1KMT2AKEAP1AKR1C3 | |
| SCHEMBL28994753 | 0.77 | TDP1 (0.62) | SLC5A1SLC5A2GAAMAPTTDP1 | |
| SCHEMBL417493 | 0.77 | KMT2A (0.69) | MAPTTDP1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL27744906 | 0.76 | KMT2A (0.56) | SLC5A1SLC5A2GAAMAPTTDP1 | |
| SCHEMBL17951284 | 0.75 | KMT2A (0.78) | MAPTTDP1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL1050111 | 0.75 | KMT2A (0.73) | MAPTTDP1KMT2AKEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662261-B | Quinone dihydrochalcone dicarboglycoside compound with glucose on ring A, preparation method and neuroprotective activity | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | claimed |
| CN-111662261-B | Quinone dihydrochalcone dicarboglycoside compound with glucose on ring A, preparation method and neuroprotective activity | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |