SCHEMBL22499185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22528727	0.89	TDP1 (0.53)	TDP1KMT2ATSHRALDH1A1KEAP1
	SCHEMBL6937307	0.82	SMN1; SMN2 (0.67)	KMT2ATSHRALDH1A1SMN1; SMN2MAPT
	SCHEMBL11527185	0.81	SMN1; SMN2 (0.71)	TDP1KMT2AALDH1A1KEAP1FFAR1
	SCHEMBL20673370	0.80	ALDH1A1 (0.50)	TDP1KMT2ATSHRALDH1A1SMN1; SMN2
	SCHEMBL16217874	0.80	ALDH1A1 (0.50)	TDP1KMT2ATSHRALDH1A1SMN1; SMN2
	SCHEMBL20869833	0.80	SMN1; SMN2 (0.48)	TDP1KMT2ATSHRALDH1A1SMN1; SMN2
	SCHEMBL28439801	0.79	AKR1C3 (0.54)	TDP1KMT2AALDH1A1NPC1RAB9A
	SCHEMBL26315892	0.79	ALDH1A1 (0.49)	TDP1KMT2AALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL27740914	0.79	TDP1 (0.42)	TDP1KMT2ATSHRALDH1A1SMN1; SMN2
	SCHEMBL9848619	0.79	KMT2A (0.43)	KMT2AALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.