Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 2/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439769 | 1.00 | KDM4E (0.50) | KDM4EMAPTTHRBALOX5APFEN1 | |
| SCHEMBL1807109 | 0.89 | TRPC6 (0.52) | KDM4EMAPTTHRBALOX5APFEN1 | |
| SCHEMBL21245878 | 0.88 | ALOX5AP (0.52) | KDM4EMAPTTHRBALOX5APFEN1 | |
| SCHEMBL21045647 | 0.87 | TRPC6 (0.63) | TRPC6 | |
| SCHEMBL30439661 | 0.87 | TRPC6 (0.63) | TRPC6 | |
| SCHEMBL21081312 | 0.85 | TRPC6 (0.56) | KDM4EMAPTTHRBTRPC6GPR119 | |
| SCHEMBL29773977 | 0.85 | TRPC6 (0.56) | KDM4EMAPTTHRBTRPC6GPR119 | |
| SCHEMBL30244696 | 0.81 | LRRK2 (0.45) | KDM4EMAPTTHRBALOX5APFEN1 | |
| SCHEMBL28812156 | 0.81 | MAPT (0.48) | KDM4EMAPTTHRBALOX5APFEN1 | |
| SCHEMBL15175760 | 0.80 | GPR119 (0.54) | KDM4EMAPTTHRBALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |