Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.47 |
| ▸ | CES1 | P23141 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901221 | 1.00 | CES2 (0.47) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL10359660 | 0.88 | CES2 (0.50) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL11804612 | 0.88 | CES2 (0.50) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL16973951 | 0.87 | CES2 (0.47) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL16973949 | 0.87 | CES2 (0.47) | CES2CES1MAPTALDH1A1KMT2A | |
| Benzoic Acid SCHEMBL28067804 | 0.86 | DAO (0.48) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL995357 | 0.85 | ALDH1A1 (0.58) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL5263495 | 0.85 | ALDH1A1 (0.58) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL995358 | 0.85 | ALDH1A1 (0.58) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL16974007 | 0.82 | CES2 (0.58) | CES2CES1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114058199-B | UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof | 深圳南科新材科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114058199-A | UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof | 深圳南科新材科技有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-114058199-B | UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof | 深圳南科新材科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-114933543-B | Synthetic method of 3-cyclopropylamino-2- (2,4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114933543-A | Synthetic method of 3-cyclopropylamino-2- (2, 4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114058199-A | UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof | 深圳南科新材科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-2481736-A1 | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | Deciphera Pharmaceuticals, LLC. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2148677-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES | Deciphera Pharmaceuticals, LLC. (US) | 2010-02-03 | — | — | EP | disclosed |
| US-20080269267-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | US | disclosed |
| WO-2008131276-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | WO | disclosed |
| US-4038281-A | CNS DEPRESSANTS, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3987051-A | Method for producing 1-unsubstituted pyrazolo[3,4-b]pyridine ketones | E. R. SQUIBB & SONS, INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269267-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | BRAF, RET, KIT | CES2 2763/4885CES1 1692/4885MAPT 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.