SCHEMBL29013097

SCHEMBL29013097

CC(F)(Oc1ncc(Br)cc1F)C(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22026488 0.81 MET (0.33)
SCHEMBL29217722 0.81 MAPT (0.32) MAPTAAK1
SCHEMBL15467385 0.80 SYK (0.35)
SCHEMBL15467427 0.75 HTT (0.31)
SCHEMBL20190439 0.73 MET (0.35) AAK1
SCHEMBL22026502 0.73 MET (0.35) AAK1
SCHEMBL20746486 0.73 MET (0.35) AAK1
SCHEMBL22866537 0.73 RXRA (0.34)
SCHEMBL29560389 0.73 RXRA (0.34)
SCHEMBL29013098 0.73 AAK1 (0.47) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116763791-A Compounds and methods of use thereof 普拉克西斯精密药物股份有限公司 2023-09-19 CN disclosed
CN-110337295-B Compounds and methods of use thereof 普拉克西斯精密药物股份有限公司 2023-06-09 CN disclosed