Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.54 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467562 | 0.93 | GRM5 (0.52) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28690316 | 0.84 | GRM5 (0.56) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL23201166 | 0.82 | CA1 (0.58) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL6805752 | 0.81 | TMEM97 (0.55) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5333413 | 0.81 | ALDH1A3 (0.52) | ALDH1A3MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL25935564 | 0.79 | GRM5 (0.51) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL30479016 | 0.79 | GRM5 (0.51) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL25256843 | 0.78 | GRM5 (0.58) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL22291054 | 0.78 | CA1 (0.55) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4941483 | 0.77 | ALDH1A3 (0.57) | ALDH1A3MEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |