Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225314 | 0.82 | MAPT (0.53) | KITMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL4941483 | 0.81 | ALDH1A3 (0.57) | ALDH1A3ALDH3A1MAPTHTTALDH1A1 | |
| SCHEMBL29013170 | 0.81 | GRM5 (0.54) | ALDH1A3ALDH3A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6225699 | 0.77 | GAA (0.52) | KITMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL3641965 | 0.76 | KIT (0.48) | KITMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL34467562 | 0.74 | GRM5 (0.52) | MAPTMAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL3554411 | 0.73 | ALDH1A1 (0.57) | MAPTMAPK1HTTALDH1A1LMNA | |
| SCHEMBL5245356 | 0.72 | MAPT (0.53) | KITMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL3804468 | 0.71 | KIT (0.45) | KITMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL3558471 | 0.71 | MAPT (0.51) | KITMAPTMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858869-A1 | ACYLATED PIPERIDINES AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094842-A1 | ACYLATED PIPERIDIHES AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-09-14 | — | — | WO | disclosed |