Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333871 | 0.92 | FFAR4 (0.41) | — | |
| SCHEMBL25935063 | 0.90 | FFAR4 (0.44) | PTGDR2MEN1KMT2ANPSR1HDAC1 | |
| SCHEMBL31639482 | 0.89 | GPR119 (0.45) | — | |
| SCHEMBL25822642 | 0.89 | MAPT (0.46) | PTGDR2CNR2MEN1KMT2ANPSR1 | |
| SCHEMBL27326706 | 0.85 | CHRM4 (0.44) | PTGDR2CNR2MEN1KMT2ANPSR1 | |
| SCHEMBL31333359 | 0.82 | TMEM97 (0.43) | PTGDR2CNR2NPSR1NPC1RAB9A | |
| SCHEMBL25031024 | 0.81 | FFAR4 (0.46) | — | |
| SCHEMBL30643706 | 0.81 | MAPT (0.45) | PTGDR2CNR2MEN1KMT2ANPSR1 | |
| SCHEMBL29013165 | 0.80 | GRM5 (0.48) | MEN1KMT2ANPSR1NPC1SMN1; SMN2 | |
| SCHEMBL30965745 | 0.80 | TRPC3 (0.42) | PTGDR2CNR2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |