Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CTSV | O60911 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443578 | 0.94 | MAOB (0.63) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL2965418 | 0.94 | MAOB (0.63) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL25920602 | 0.91 | MAOB (0.64) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL25920598 | 0.90 | MAPT (0.62) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL7356754 | 0.87 | AR (0.60) | MAOBMAPTMEN1KMT2ALMNA | |
| Acetonitrile SCHEMBL28336082 | 0.86 | MAOB (0.62) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL2872357 | 0.86 | MEN1 (0.58) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL17554366 | 0.85 | MAOB (0.73) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL6599866 | 0.85 | MAOB (0.68) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL13192710 | 0.84 | MAOB (0.70) | MAOBALDH1A1MAOACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217476-A | Quinolone compounds with anti-new coronavirus activity and application thereof in medicines | 中国药科大学 | 2023-06-06 | — | — | CN | disclosed |