Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | CTSV | O60911 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | TLR4 | O00206 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965418 | 0.97 | MAOB (0.63) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL30443578 | 0.97 | MAOB (0.63) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL25920598 | 0.93 | MAPT (0.62) | MAOBMAOAMAPTMEN1KMT2A | |
| Hydroquinone SCHEMBL29014236 | 0.91 | MAOB (0.61) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL6599866 | 0.91 | MAOB (0.68) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL7356754 | 0.90 | AR (0.60) | MAOBMAOAMAPTMEN1KMT2A | |
| Acetonitrile SCHEMBL28336082 | 0.89 | MAOB (0.62) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL2872357 | 0.88 | MEN1 (0.58) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL810521 | 0.85 | MAOB (0.63) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL4747135 | 0.85 | MAPT (0.55) | MAOBMAOAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | MAOB 4046/4885MAOA 4417/4885MAPT 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.