Sulfamate

Sulfamate

SCHEMBL29014381

CC(O)CNCCNCCO.NS(=O)(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.34
ALDH1A1 P00352 4/20 0.32
MEN1 O00255 4/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
ADRB2 P07550 1/20 0.32
USP2 O75604 2/20 0.32
LMNA P02545 2/20 0.32
TP53 P04637 2/20 0.32
MAPK1 P28482 2/20 0.32
RECQL P46063 2/20 0.32
BLM P54132 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
CACNA1F O60840 1/20 0.32
SLC22A3 O75751 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamate SCHEMBL28991733 0.96 KMT2A (0.33) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
Sulfamate SCHEMBL30352768 0.90 KMT2A (0.39) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
Sulfamate SCHEMBL30352769 0.90 KMT2A (0.39) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
SCHEMBL11143488 0.88 ADRB2 (0.35) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
SCHEMBL6865618 0.86 KMT2A (0.41) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
SCHEMBL4630313 0.86 KMT2A (0.41) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
SCHEMBL11142127 0.85 ALDH1A1 (0.33) KMT2AALDH1A1MEN1SMN1; SMN2ADRB2
SCHEMBL17941722 0.82
SCHEMBL1425004 0.82
SCHEMBL3509339 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN claimed
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN disclosed