Sulfamate

Sulfamate

SCHEMBL29014386

CC(CN)NCCO.NS(=O)(=O)O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.32
NT5E P21589 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613351 0.87
Fluoride SCHEMBL6762574 0.85 SLC6A4 (0.39) SLC6A4HSD17B10
Sulfuric Acid SCHEMBL1344257 0.77 SLC6A4 (0.37) SLC6A4HSD17B10
Sulfamate SCHEMBL29014371 0.77 SLC6A4 (0.30) SLC6A4
Sulfamate SCHEMBL29014383 0.77
SCHEMBL11742875 0.74
SCHEMBL28038414 0.73 SLC6A4 (0.35) SLC6A4HSD17B10
SCHEMBL28038447 0.73 SLC6A4 (0.35) SLC6A4HSD17B10
SCHEMBL11142806 0.72 LMNA (0.35) SLC6A4HSD17B10
SCHEMBL12249052 0.71 SIGMAR1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN claimed
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN disclosed