SCHEMBL29014454

SCHEMBL29014454

CC#COC(=O)c1ncc[nH]1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
KMT2A Q03164 1/20 0.38
GLA P06280 1/20 0.35
BRAF P15056 1/20 0.35
HDAC1 Q13547 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
HSPA5 P11021 1/20 0.32
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8414889 0.81 NPC1 (0.43) NPC1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL262815 0.77
SCHEMBL31229951 0.77 NPC1 (0.47) NPC1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL263485 0.74 NPC1 (0.46) NPC1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL5317101 0.73
SCHEMBL6270339 0.73
SCHEMBL2429665 0.73 NPC1 (0.45) NPC1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL152733 0.73 NUDT1 (0.49) NPC1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL179869 0.72 NPC1 (0.44) NPC1RAB9AALDH1A1KDM4EKMT2A
Bromide SCHEMBL29572453 0.71 NUDT1 (0.48) NPC1RAB9AALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703741-B Preparation method and application of imidazole carboxylic acid ester 张家港市国泰华荣化工新材料有限公司 2024-04-26 CN disclosed
CN-116082243-A Preparation method of unsaturated hydrocarbyloxycarbonyl imidazole 苏州祺添新材料有限公司 2023-05-09 CN disclosed
CN-115703741-A Preparation method and application of imidazole carboxylate 张家港市国泰华荣化工新材料有限公司 2023-02-17 CN disclosed