Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL28321978 | 0.88 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL9139120 | 0.84 | NPC1 (0.42) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL5838309 | 0.82 | NPC1 (0.42) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL4636002 | 0.82 | NPC1 (0.40) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL262815 | 0.79 | — | — | |
| Ornithine SCHEMBL3801714 | 0.78 | GSR (0.39) | NPC1RAB9A | |
| SCHEMBL5164159 | 0.78 | NPC1 (0.40) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL31229951 | 0.78 | NPC1 (0.47) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL6858144 | 0.77 | RAB9A (0.39) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL23367084 | 0.75 | L3MBTL1 (0.41) | NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494162-A1 | NON-TIN CATALYST FOR CURING ALKOXYSILYL-CONTAINING POLYMER | Momentive Performance Materials Inc. (US) | 2019-06-12 | — | — | EP | claimed |
| WO-2018049375-A1 | NON-TIN CATALYST FOR CURING ALKOXYSILYL-CONTAINING POLYMER | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-03-15 | — | — | WO | claimed |
| WO-2008082224-A1 | WATER-SOLUBLE PHOTOINITIATORS | INKTEC CO., LTD. (KR) | 2008-07-10 | — | — | WO | claimed |
| EP-1218338-A1 | PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES | ABBOTT LABORATORIES (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001027074-A1 | PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES | ABBOTT LABORATORIES (US) | 2001-04-19 | — | — | WO | claimed |
| EP-0211580-A2 | Renin inhibiting polypeptides and intermediates therefor | PFIZER INC. (US) | 1987-02-25 | — | — | EP | claimed |
| US-20250340567-A1 | Next Generation Synthetic Transcription Factors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250282621-A1 | CARBON NANOTUBE COMPOSITE COMPRISING MECHANICAL L IGANDS | NANOCORE APS (DK) | 2025-09-11 | — | — | US | disclosed |
| US-20250145731-A1 | LINKER FOR ANTIBODY-DRUG CONJUGATES AND ITS USE | REMEGEN CO., LTD. (CN) | 2025-05-08 | — | — | US | disclosed |
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| US-12195552-B2 | Linker for antibody-drug conjugates and its use | REMEGEN CO., LTD. (CN) | 2025-01-14 | — | — | US | disclosed |
| EP-3868409-B1 | THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS | REMEGEN CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| EP-4363373-A1 | CARBON NANOTUBE COMPOSITE COMPRISING MECHANICAL LIGANDS | Nanocore ApS (DK) | 2024-05-08 | — | — | EP | disclosed |
| US-4857513-A | Diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISIWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4729985-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1988-03-08 | — | — | US | disclosed |
| US-4725680-A | AMINATION, CLEAVAGE, NEUTRALIZATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-02-16 | — | — | US | disclosed |
| EP-0243173-A2 | New diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0212903-A2 | Polypeptide derivatives containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1987-03-04 | — | — | EP | disclosed |
| CN-85101512-A | PROCESS FOR PREPARING CARBAMIC ACID DERIVATIVES | — | 1987-01-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | HIPK1, NEK1, HIPK2 | NPC1 1141/4885RAB9A 2380/4885ALDH1A1 2398/4885 |
| US-12195552-B2 | Linker for antibody-drug conjugates and its use | PA2G4, IGSF11, FCGRT | NPC1 4648/4885RAB9A 3867/4885ALDH1A1 321/4885 |
| US-20250340567-A1 | Next Generation Synthetic Transcription Factors | ZFX, RUNX1, JUN | NPC1 3622/4885RAB9A 4063/4885ALDH1A1 4799/4885 |
| US-20250145731-A1 | LINKER FOR ANTIBODY-DRUG CONJUGATES AND ITS USE | PA2G4, IGSF11, FCGRT | NPC1 4648/4885RAB9A 3867/4885ALDH1A1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.