Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 7/20 | 0.36 |
| ▸ | MMP2 | P08253 | 7/20 | 0.36 |
| ▸ | MMP9 | P14780 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250636 | 0.95 | ACKR3 (0.38) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL29015151 | 0.86 | ACKR3 (0.41) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL25256819 | 0.84 | ACKR3 (0.42) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL29410356 | 0.82 | KDM1A (0.45) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL25246315 | 0.82 | ACKR3 (0.41) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL29410364 | 0.82 | ACKR3 (0.41) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL25249510 | 0.82 | KDM1A (0.45) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL25249882 | 0.82 | ACKR3 (0.41) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL25250405 | 0.82 | KDM1A (0.45) | KDM1AACKR3HDAC1HDAC2MMP1 | |
| SCHEMBL29410333 | 0.82 | KDM1A (0.45) | KDM1AACKR3HDAC1HDAC2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096712-A | Novel compounds | NRG治疗有限公司 | 2023-05-09 | — | — | CN | disclosed |