Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298988 | 0.95 | ACKR3 (0.42) | ACKR3HDAC1HDAC2MAOAMAOB | |
| SCHEMBL25252295 | 0.95 | ACKR3 (0.42) | ACKR3HDAC1HDAC2MAOAMAOB | |
| SCHEMBL29015149 | 0.86 | KDM1A (0.37) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL25256819 | 0.85 | ACKR3 (0.42) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL25249510 | 0.83 | KDM1A (0.45) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL29410356 | 0.83 | KDM1A (0.45) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL25250405 | 0.83 | KDM1A (0.45) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL25249882 | 0.83 | ACKR3 (0.41) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL25246315 | 0.83 | ACKR3 (0.41) | ACKR3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL29410333 | 0.83 | KDM1A (0.45) | ACKR3HDAC1HDAC2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096712-A | Novel compounds | NRG治疗有限公司 | 2023-05-09 | — | — | CN | disclosed |