Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.36 |
| ▸ | TSHR | P16473 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 8/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467747 | 0.98 | NPC1 (0.43) | NPC1RAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252842 | 0.98 | NPC1 (0.43) | NPC1RAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30451465 | 0.88 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29015646 | 0.88 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252333 | 0.82 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30467624 | 0.82 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252477 | 0.82 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30452368 | 0.82 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252927 | 0.80 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30451545 | 0.80 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |