Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20536245 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ASTK39KMO | |
| SCHEMBL20536246 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ASTK39KMO | |
| SCHEMBL29015520 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ASTK39KMO | |
| SCHEMBL30396850 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ASTK39KMO | |
| SCHEMBL24189544 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ASTK39KMO | |
| SCHEMBL19343270 | 0.87 | SCD (0.38) | HPGDALDH1A1LMNA | |
| SCHEMBL20535659 | 0.87 | HDAC8 (0.40) | SMN1; SMN2NPC1RAB9AHDAC8HPGD | |
| SCHEMBL23709920 | 0.87 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9AHDAC8HPGD | |
| SCHEMBL20535655 | 0.87 | HDAC8 (0.40) | SMN1; SMN2NPC1RAB9AHDAC8HPGD | |
| SCHEMBL30396596 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2NPC1RAB9AHDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |