Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015520 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKMOHDAC8 | |
| SCHEMBL24189544 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKMOHDAC8 | |
| SCHEMBL20536246 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKMOHDAC8 | |
| SCHEMBL20536245 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKMOHDAC8 | |
| SCHEMBL29015479 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKMOHDAC8 | |
| SCHEMBL29015530 | 0.89 | KMO (0.39) | KMOHDAC8HDAC1HDAC6PGR | |
| SCHEMBL30396183 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL20535655 | 0.84 | HDAC8 (0.40) | SMN1; SMN2NPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL20535659 | 0.84 | HDAC8 (0.40) | SMN1; SMN2NPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL23709920 | 0.84 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9AHDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |