Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113456 | 0.87 | MAPT (0.38) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL30009048 | 0.87 | MAPT (0.38) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL29015469 | 0.83 | RORC (0.36) | KMT2AMEN1IRAK4 | |
| SCHEMBL24190445 | 0.83 | RORC (0.36) | KMT2AMEN1IRAK4 | |
| SCHEMBL23709904 | 0.83 | RHEB (0.35) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24113473 | 0.82 | CYP11B1 (0.34) | KMT2ACYP11B1ALDH1A1POLB | |
| SCHEMBL30008870 | 0.82 | CYP11B1 (0.34) | KMT2ACYP11B1ALDH1A1POLB | |
| SCHEMBL20536123 | 0.81 | L3MBTL1 (0.39) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL20536125 | 0.81 | L3MBTL1 (0.39) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL29062727 | 0.81 | ANO1 (0.34) | KMT2AMEN1CYP11B1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |