Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607435 | 0.83 | PDE3B (0.46) | AHRGRIA1CACNG8MEN1KMT2A | |
| SCHEMBL29016213 | 0.81 | AHR (0.48) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL28597925 | 0.81 | AHR (0.43) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL29016210 | 0.81 | AHR (0.47) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL28614212 | 0.79 | SMN1; SMN2 (0.43) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL6431 | 0.78 | AHR (0.72) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL28607810 | 0.78 | AHR (0.47) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL29016211 | 0.77 | CRBN (0.53) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL28606054 | 0.77 | AHR (0.40) | AHRCMA1GRIA1CACNG8TDP2 | |
| SCHEMBL28597906 | 0.76 | EIF2AK2 (0.50) | AHRCMA1TDP2HSD17B10CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |