SCHEMBL29016384

SCHEMBL29016384

Cc1ccc(N2C(=O)c3ccccc3C2=S)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
KMT2A Q03164 5/20 0.57
MEN1 O00255 4/20 0.57
GAA P10253 2/20 0.57
TLR9 Q9NR96 1/20 0.57
PGR P06401 1/20 0.55
ADORA2A P29274 1/20 0.54
DPP4 P27487 1/20 0.53
NR1H2 P55055 1/20 0.53
NR1H3 Q13133 1/20 0.53
F2 P00734 1/20 0.50
ELANE P08246 1/20 0.50
CTSG P08311 1/20 0.50
CMA1 P23946 1/20 0.50
CTRC Q99895 1/20 0.50
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
TSHR P16473 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11836683 0.92 KMT2A (0.59) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL6926171 0.86 NR1H3 (0.53) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL30472945 0.86 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL325212 0.86 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL11105064 0.84 PGR (0.53) KMT2AMEN1GAAPGRDPP4
SCHEMBL28673973 0.84 KMT2A (0.50) KMT2AMEN1GAADPP4NR1H2
SCHEMBL11844877 0.82 NR1H3 (0.53) KMT2AMEN1DPP4NR1H2NR1H3
SCHEMBL11842657 0.80 NR1H3 (0.48) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL28812426 0.78 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1GAATLR9
SCHEMBL29842449 0.78 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1GAATLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253670-A Method for introducing alkynyl disulfide bond at mercapto end 山西蓬勃健康科技有限公司 2023-06-13 CN disclosed