SCHEMBL29016393

SCHEMBL29016393

CCCCC#CN1C(=O)c2ccccc2C1=S

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.39
NR1H2 P55055 2/20 0.38
NR1H3 Q13133 2/20 0.38
ASAH1 Q13510 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ALDH2 P05091 1/20 0.36
ALDH3A1 P30838 1/20 0.36
CES1 P23141 2/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
CDC25A P30304 1/20 0.35
DPP4 P27487 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10871583 0.89 DRD3 (0.44) DRD3NR1H2NR1H3ASAH1ALDH1A1
SCHEMBL5069988 0.84 NR1H2 (0.44) DRD3NR1H2NR1H3ASAH1ALDH1A1
SCHEMBL900640 0.79 DRD3 (0.46) DRD3NR1H2NR1H3ASAH1ALDH1A1
SCHEMBL613586 0.72 DRD3 (0.44) DRD3ALDH1A1CA12CA9RAB9A
SCHEMBL11455316 0.70 NPC1 (0.53) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL20422074 0.70 DPP4 (0.41) DRD3NR1H2NR1H3CA12CA9
SCHEMBL29016391 0.70 DRD3 (0.41) DRD3NR1H2NR1H3ASAH1ALDH1A1
SCHEMBL11219595 0.69 ALDH1A1 (0.58) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL29016413 0.69 DPP4 (0.40) DRD3NR1H2NR1H3ALDH1A1CA12
SCHEMBL10930457 0.68 CDC25A (0.59) ALDH1A1ALDH2ALDH3A1CES1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375620-B Method for synthesizing acyl disulfide compound through solvent-free rearrangement reaction 山西蓬勃健康科技有限公司 2025-03-18 CN disclosed
CN-116375620-A Method for synthesizing acyl disulfide compound through solvent-free rearrangement reaction 山西蓬勃健康科技有限公司 2023-07-04 CN disclosed
CN-116253670-A Method for introducing alkynyl disulfide bond at mercapto end 山西蓬勃健康科技有限公司 2023-06-13 CN disclosed