Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | BMI1 | P35226 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30369993 | 0.86 | CNR2 (0.44) | MEN1KMT2APOLBCNR2BMI1 | |
| SCHEMBL29016582 | 0.86 | CNR2 (0.44) | MEN1KMT2APOLBCNR2BMI1 | |
| SCHEMBL29016571 | 0.82 | CNR2 (0.41) | MEN1KMT2APOLBCNR2HTT | |
| SCHEMBL29016631 | 0.81 | RORC (0.46) | CNR2CNR1 | |
| SCHEMBL29016659 | 0.80 | CYP11B1 (0.43) | MEN1KMT2ABMI1HTTMAPT | |
| SCHEMBL29016550 | 0.78 | RORC (0.40) | ALDH1A1 | |
| SCHEMBL30370349 | 0.78 | POLB (0.38) | MEN1KMT2APOLBCNR2CNR1 | |
| SCHEMBL30370131 | 0.72 | RORC (0.50) | CNR2CNR1 | |
| SCHEMBL29016565 | 0.72 | RORC (0.50) | CNR2CNR1 | |
| SCHEMBL15552105 | 0.68 | TP53 (0.42) | MEN1KMT2AHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |