Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016631 | 0.84 | RORC (0.46) | CNR2RORC | |
| SCHEMBL29016550 | 0.83 | RORC (0.40) | PPARGLMNARORC | |
| SCHEMBL29016642 | 0.82 | MEN1 (0.41) | CNR2POLBMEN1KMT2ARAB9A | |
| SCHEMBL29016636 | 0.74 | KDM4E (0.40) | MEN1KMT2ALMNARAB9AHTT | |
| SCHEMBL29016565 | 0.74 | RORC (0.50) | CNR2RORC | |
| SCHEMBL30370131 | 0.74 | RORC (0.50) | CNR2RORC | |
| SCHEMBL4529355 | 0.72 | MEN1 (0.36) | CNR2POLBMEN1KMT2ALMNA | |
| SCHEMBL15552105 | 0.72 | TP53 (0.42) | PPARGMEN1KMT2ALMNANPSR1 | |
| SCHEMBL14247220 | 0.71 | DHFR (0.41) | MEN1KMT2ALMNARAB9AHTT | |
| SCHEMBL12853410 | 0.71 | FABP4 (0.48) | MEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |