SCHEMBL29017405

SCHEMBL29017405

NCCC1(c2ccccc2)COC1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.50
MAOA P21397 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
DPP4 P27487 2/20 0.47
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GRIN1 Q05586 3/20 0.41
GRIN2A Q12879 3/20 0.41
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
OPRM1 P35372 1/20 0.36
OPRL1 P41146 1/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16296466 0.83 MAOB (0.65) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL29374849 0.81 MAOA (0.68) MAOBMAOATAAR1DPP4KDM4E
SCHEMBL15577225 0.81 MAOA (0.52) MAOBMAOATAAR1DPP4KDM4E
SCHEMBL5031526 0.80 MAOA (0.41) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL3380377 0.80 ACSS2 (0.43) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL10208913 0.78 DPP4 (0.70) MAOBMAOATAAR1DPP4SLC6A2
SCHEMBL3377295 0.77 EPHX2 (0.40) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL1561557 0.77 MAOA (0.45) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL12086616 0.76 MAOB (0.50) MAOBMAOATAAR1DPP4KDM4E
SCHEMBL2864514 0.76 DPP4 (0.68) MAOBMAOATAAR1DPP4GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116240194-A Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2023-06-09 CN disclosed