SCHEMBL29017461

SCHEMBL29017461

CC(=O)c1ccc(C=O)c(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.40
PRKDC P78527 1/20 0.40
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 2/20 0.40
CYP2A6 P11509 1/20 0.39
CRHR1 P34998 2/20 0.39
PKM P14618 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.38
ERN1 O75460 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1174942 0.82 ERN1 (0.47) SMN1; SMN2NPC1RAB9AKMT2AMAPT
SCHEMBL29848550 0.82 ERN1 (0.47) SMN1; SMN2NPC1RAB9AKMT2AMAPT
SCHEMBL25128750 0.82 KMT2A (0.45) SLC2A1SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL205064 0.80 NOTUM (0.55) MAPTALDH1A1KDM4EL3MBTL1HSD17B10
SCHEMBL11585526 0.78 TYR (0.52) SLC2A1NPC1RAB9AKMT2AMAPT
SCHEMBL16769475 0.78 CYP2A6 (0.44) SLC2A1NPC1RAB9AKMT2AMAPT
SCHEMBL3022646 0.77 MAPT (0.47) SMN1; SMN2NPC1RAB9AKMT2AMAPT
SCHEMBL4778686 0.77 PRKCI (0.53) SLC2A1NPC1RAB9AKMT2AMAPT
SCHEMBL12703704 0.77 ERN1 (0.42) SLC2A1SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL2353178 0.77 HPGD (0.55) SMN1; SMN2NPC1RAB9AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116262976-B Electrochemical synthesis method of benzaldehyde derivative 国科大杭州高等研究院 2024-04-05 CN disclosed
CN-116262976-A Electrochemical synthesis method of benzaldehyde derivative 国科大杭州高等研究院 2023-06-16 CN disclosed